Androgen insensitivity syndrome

Werewolves did not receive the same revisionist treatment as vampires did during the ’90s, partly due to the high probability of Special Effect Failure in visual media, but also because the concept is much more difficult to rehabilitate. While having your neck bitten by beautiful people is erotic, being torn into bloody chunks and eaten is not. And in most common depictions, werewolves aren’t exactly sapient in wolf form. Surprisingly, such an earlier revisionist treatment happened in medieval times for fictitious werewolves; in the Chivalric Romance , a werewolf could be a perfectly gentle and noble beast. Recently the werewolf’s cachet has been rising. And they are very popular within the Furry Fandom , usually of the more-in-control-while-transformed variety, and their depictions therein can range from the innocent to outright Yiff. The word “werewolf” is a compound with the archaic English word wir. Etymologically, “man” was once genderless, and “wir” meant a male adult. Compare this to latin ‘vir’ where we get the words “virile”, and “virtue”.

What does it feel like to have Klinefelters’ syndrome?

Share He was prescribed three-monthly testosterone injections, which he now has to have for life. It was after the second jab that Paul noticed his sex drive returning and his other symptoms disappearing. Now, four years after his problems began, Susan says she and Paul make love up to five times a week. It was like having the Paul I first met back again.

I’m so glad it could be sorted – those months were the worst period of our marriage. There’s evidence that more and more men are suffering from a low libido.

Testosterone T enters the cell and, if 5-alpha-reductase is present, is converted into dihydrotestone DHT.

KS only effects boys, to this day nobody is quite sure what causes it, though there is a strong belief it is caused by a mutant sperm. Detection within the womb is difficult, but there is supposed to be blood tests taken within 16 weeks of pregnancy or 24 weeks in older moms, the test is called a Karyotype blood test, and this checks for chromosome counts etc. If, however the test wasn’t given through pregnancy, and the boy child is fortunate enough to be diagnosed at a very young age pre-puberty , then his treatment and support needs are installed rapidly to try and counter the extreme effects of KS upon reaching puberty.

The first years of his life are relatively calm, though there will be times he will be withdrawn, a loner, mis-labelled at school by the education authorities as being slow or simple, he will be unable to communicate verbally, ie trying to explain things or engage in conversation, he will suffer bouts of frustration based outbursts, verbally or violently.

Now this is with the treatment, care and support, and there are a great many other issues the boy will suffer but his outside appearance and mannerisms will be nothing compared to the conflict and suffering he has inside. Upon reaching puberty he should have been on testosterone replacement therapy prior to pubecence and this would help he move forward physically as well as mentally into youth and maturity. Alas, many KS boys are not diagnosed at a young age or pre-puberty, but in adulthood, and the damage is irreversible.

There is no cure for KS, no wonder drugs to make it all go away, it is a life-long illness and likely the cause of eventual death.

Klinefelter’s Syndrome XXY – Klinefelter Syndrome Defined

It is a new option in prenatal screening for Down syndrome Trisomy 21 and other fetal chromosomal conditions Trisomies 18 and 13 , X and Y chromosome conditions. This test can be requested for any singleton pregnancy, including in vitro fertilization IVF pregnancies with egg donors. Cell free DNA cfDNA results from the natural breakdown of fetal cells presumed to be mostly placental and clears from the maternal system within hours of giving birth. During a pregnancy, cfDNA can be tested to give the most accurate screening approach in estimating the risk of fetus having a common chromosome condition sometimes called a trisomy.

Okami Kakushi has the “Jouga Wolves”, a legendary race of wolves that have become indistinguishable from humans in appearance.

Role and Risk Factor for Cancer Treatment Views 0 Comments The body is made up of millions of cells and cancer starts when one of them instigates to develop and proliferate too much resulting to make a growth called tumour. Over the decades cancer shows high incidence of death and different therapy technique develop including radiotherapy and chemotherapy. However, recent discovery about hyperthermia technique which… 05 Canadian system for outdoor air monitoring Views 90 Comments Aerobiology Research was first formed in to collect outdoor air samples and report on pollen and fungal spore levels.

We started with 12 sites across Canada and now have 30 where samples are gathered and our laboratory analysis is done. The database we have collected is also stored in our laboratory in Ottawa for… 02 Fall and Winter Allergies Views 33 Comments Well, the outdoor allergy season is almost over and we will soon be finished doing collections and providing information to the public through our reports that we produce.

The pollen in the air is generally at low levels or even absent on many days now. But people may still be suffering for a while in… 23 A Symbiont Betrays Its Host Views 56 Comments It came as a surprise to me recently to realize how much is known about the immune responses of plants and, moreover, how much there is to know.

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Are There Women Who’ll Date A Man With Ks

I had itching issues since grade 2 and was never diagnosed until I had never paid attention to the appearance of my vag until the diagnosis. I have absolutely no inner labia left and my clitorial hood is completely fused over. I’m 38 and had to get 3 csections because of this because I couldn’t have a vag birth. I can still orgasm but the skin around the clit fissures and splits. The skin around the opening gets itchy and raw.

The testing is non-invasive:

I have met some XXY guys who have led a similar life to mine, but not identical. I just deleted an entire comment that I thought was pretty good, but oh well, it’s not an XXY trait, it’s human. XXY males are human. In my life I have met many people who were abused by their parents, and other people. I have met many people who were abused at school, called bullying.

I have met XXY’s who are bullies. Are these human or XXY traits? I have met XXY guys who are really clever, laywers, accountants, clergy. I have met XXY guys who are like me, gardeners.

Human health and biology

What is Klinefelter syndrome? How do I support a partner who has it? He was very blunt and upfront with his condition.

I don’t have that problem now as I sought a remedy, and found one.

Julio 23, a las 2: This obstruction damages liver cells and leads to scarring called cirrhosis. Calcitonin a thyroid hormone is used to treat osteoporosis. BP pulse RR oxygen saturation on L of oxygen via nasal cannula. If the diagnosis is established patient has four of the seven criteria in Box Diagnosis of Rheumatoid Arthritis then refer the patient to a rheumatologist for initiation of diseasemodifying therapy.

However the potential array of disruptions in histone modication and chromatin states which result from these mutations and from additional defects in chromatin regulators found in other nervous system diseases is much more diverse and multifaceted and thus less well characterized than DNA methylation abnormalities. The analysis was based mainly on the outcomes of clinical series.

Living With XXY/Klinefelter Syndrome

Transvaginal ultrasound is performed using a special transducer which is slightly thicker than a tampon. It is covered with a disposable latex sheath and lubricating gel, then gently placed into the vagina. The probe sits in the vagina throughout the examination which usually takes between minutes.

We called the doctor to find out those results from tests we had taken 3 yrs ago.

Genetics[ edit ] Location and structure of the human androgen receptor: Top, the AR gene is located on the proximal long arm of the X chromosome. Middle, the eight exons are separated by introns of various lengths. Bottom, illustration of the AR protein, with primary functional domains labeled not representative of actual 3-D structure. Several case studies of fertile 46,XY males with AIS have been published, [4] [60] [61] [62] [63] although this group is thought to be a minority.

A genetic female conceived in such a way would receive her father’s X chromosome, thus would become a carrier. A mutation in one but not both results in a minimally affected, fertile, female carrier. If the affected child is a genetic female, she, too, will be a carrier. A genetic female with mutations in both AR genes could theoretically result from the union of a fertile man with AIS and a female carrier of the gene, or from de novo mutation. However, given the scarcity of fertile AIS men and low incidence of AR mutation, the chances of this occurrence are small.

The phenotype of such an individual is a matter of speculation; as of , no such documented case has been published. Correlation of genotype and phenotype[ edit ] Individuals with partial AIS, unlike those with the complete or mild forms, present at birth with ambiguous genitalia , and the decision to raise the child as male or female is often not obvious.

Pregnancy, Trying to conceive & Parenting Forum

Human karyotype[ edit ] human karyotype The normal human karyotypes contain 22 pairs of autosomal chromosomes and one pair of sex chromosomes allosomes. Any variation from the standard karyotype may lead to developmental abnormalities. Diversity and evolution of karyotypes[ edit ] Although the replication and transcription of DNA is highly standardized in eukaryotes , the same cannot be said for their karyotypes, which are highly variable.

They got to the point where Lucy was reluctant even to give Stuart a cuddle in case she faced yet another rejection.

He is 6′ 6″, , and has large breasts. He also has under-developed testicles and penis. He revealed all this to me when we began dating, along with his infertility. We have been married for 17 years now I was young and recently divorced with two little girls of my own, so the Infertility wasn’t that important to me.

I went I to this marriage knowing that sex would not be ” the same” for me for the rest of my life, but I decided I could live with that. Good luck finding love. Don’t give up – if you are attracted to someone, try to get to know them and see what happens. Large breast can be due to being overweight. And some men just have underdeveloped genitals.

Not saying he doesn’t have kf.

Our Werewolves Are Different

Screening can be performed any time from 10 weeks of pregnancy. All testing is undertaken in our fully accredited genetic laboratories and results are available in business days from sample receipt. Your test results are analysed by accredited medical scientists who are trained as specialists in prenatal screening and diagnosis.

Screening is safe and poses no threat to the pregnancy because it uses a simple blood sample collected from the mother. NIPT is the most accurate prenatal screening test for Down syndrome. There is no upper gestation limit for testing, but the ideal time is between weeks.

He wants sex and that’s all there is to it.

Originally Posted by theclarks I know this may not be a politically correct statement but I have always felt Klinefelters’s was by far worse then azoospermia. Including my husband feeling like he is part woman. Let me tell you alil more from the beginning. I met my hubby in later and by March we were married. I know I was too young at the time 19 but I was always hoping we would fall pregnant.

It wasnt until Dec that we decided to really start trying.